The current environment for CA SDM uses OLE DB set at 4k to read/write from SQL Server. Microsoft states best practice for SQL Server 2008+ is to use 64k disk block sizes for the best I/O performance. See the following articles:
The current OLE-DB used to communicate to SQL Server is hard coded to 4k and is not configurable by the customer. A configuration that can be changed and extended so the OLE-DB bandwidth is equal to the block size on the SQL Server is the best configuration for optimal performance. In order to optimize performance of SQL Server 2008, a method to allow 64k disk blocks to be used with CA SDM is desired.