Create a dummy query first, e.g. (Hostname = 'without software').
Then right click this entry in the right pane of the Query Designer, select Edit SQL and replace the SQL by:
ca_discovered_hardware.asset_Source_Uuid not in (
select distinct soft.asset_Source_Uuid
from Ca_Discovered_Software soft)
and ca_discovered_hardware.dis_Hw_Uuid in (
select member_Uuid
from Ca_Group_Member
where group_Uuid = 0x849b57d5c96b4d4989f3f99a0a8e3d83) order by 1