Yes, there are ways to resolve this:
- review your server.conf file, especially the virtual hosts section
- review your httpd.conf, and ensure that the ports and listeners are alright
- I always suggest that you troubleshoot from first principles - trace the HTTP request along, to see how far it has proceeded (whether it has reached the HTTPD server, the Proxy Engine, and then the agent on the Proxy Engine etc.)
- open a ca support ticket