Hi Vijay, long time!
The recommendation is always to have your collectors as close to the applications as possible to reduce latency issues. Remember that the agents are bursting data every 7.5 seconds.
The other question becomes where the SolMan is. Is the thought to have a single one or two?
Last, but not, least, how will you manage the view of data? a single MOM EM or multiple? Do you need to unify the view of data across the DCs?
I can provide some additional feedback based upon your responses.
-Hiko