Normally when this error occurs it is because of a permissions issue on the {{LISA_HOME}}\Projects folder. Unless you have modified the res-hub-config.properties file to point to a different folder, then it is that folder that needs to have the permissions open.
If the Portal is running on Windows, right-click in the {{LISA_HOME}} folder, choose Properties, choose the Security tab, choose Edit, highlight the User Group, make sure Full control and Modify check boxes are set to true,, then click the Apply.
If the Portal is running on Linux, do a chmod -R 777 on the {{LISA_HOME}} folder.
Let me know if this helps.
~Marcy