So you are referring this in web.cfg....
# RedirectingURL specifies the full URL for redirecting the request to
# the webengine. By default, it uses 'CAisd' and the value set for the
# Cgi variable to construct the URL.
# If this webengine uses SSL connection, the protocol, https, needs to
# be added to the URL, for example,
# RedirectingURL https://<machine name>/<cgi directory>/<cgi name>
RedirectingURL http://servicedesk2.test.co.in/CAisd/pdmweb.exe
does it require service restart ?